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Saturday, July 24, 2021

 NI-KSHAY-(Ni=End, Kshay=TB) is the web enabled patient management system for TB control under the National Tuberculosis Elimination Programme (NTEP). It is developed and maintained by the Central TB Division (CTD), Ministry of Health and Family Welfare, Government of India, in collaboration with the National Informatics Centre (NIC), and the World Health Organization Country office for India.

Nikshay is used by health functionaries at various levels across the country both in the public and private sector, to register cases under their care, order various types of tests from Labs across the country, record treatment details, monitor treatment adherence and to transfer cases between care providers. It also functions as the National TB Surveillance System and enables reporting of various surveillance data to the Government of India.

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Friday, July 23, 2021

Nikshay aushadhi introduction



Nikshay Aushadhi Mobile App (updated version 1.2.9) is available to download from Google Play Store. 



APPLICATION FEATURES

Alert Management

A utility purposed to broadcast information, managing event based and job based alerts and governing the pending tasks as soon as user login into system.


Digital Signature

Eliminating the possibility of human error, assuring security and improving the legal weight by signing documents digitally.


Data Analysis

Tracking the present actions or going on; rather rational analysis of past and present data to approach a better future predictions.


Dynamic Reports

Dynamic reports with its irresolute formats proved to be beneficial handling dynamic data.




Introduction

National Tuberculosis Elimination Program(NTEP) aims for achieving universal access to TB diagnosis and treatment. Over the years, the programme has expended its service of TB and drug resistant TB across the country with access to free diagnosis and anti-TB drugs. The programme is now striving to achieve standards for Tb care in India across all sectors of health care providers.


The National Strategic Plan (NSP) sets out the strategic direction and key initiatives that the Ministry of Health and Family Welfare will undertake from 2017 to 2025 for working towards achieving the goals of eliminating TB by 2025. We have seen excellent commitment and the progress achieved through the previous NSP period, yet much more is required to be done to accelerate the march towards a TB free India.


Continuous and smooth supply of good quality assured Anti TB Drugs and all related commodities is an essential activity under NTEP. The procurement of Anti TB drugs, equipment and diagnostics is planned, coordinated and done centrally on an annual basis through a well-defined procurement mechanism.




National Tuberculosis Elimination Program(NTEP) aims for achieving universal access to TB diagnosis and treatment. Over the years, the programme has expended its service of TB and drug resistant TB across the country with access to free diagnosis and anti-TB drugs. The programme is now striving to achieve standards for Tb care in India across all sectors of health care providers.


The National Strategic Plan (NSP) sets out the strategic direction and key initiatives that the Ministry of Health and Family Welfare will undertake from 2017 to 2025 for working towards achieving the goals of eliminating TB by 2025. We have seen excellent commitment and the progress achieved through the previous NSP period, yet much more is required to be done to accelerate the march towards a TB free India.


Continuous and smooth supply of good quality assured Anti TB Drugs and all related commodities is an essential activity under NTEP. The procurement of Anti TB drugs, equipment and diagnostics is planned, coordinated and done centrally on an annual basis through a well-defined procurement mechanism.


Several initiatives have been taken to enable uninterrupted supply of good quality diagnostics and anti TB drugs to all TB patients. 2500 LED microscopes were procured, along with 1235 CBNAAT machines and 7.8 lakhs cartridges to expand the reach of quality diagnostics across the country and strengthen district level diagnostic capacities.


To enhance the implementation of Nikshay Aushadhi, NIKSHAY and other related activities under NTEP, the Programme has successfully finalized the procurement of 20K of Tablets. The Tablet Computers will be distributed at Central and State levels like Programme & GMSDs officials, State TB Officer, State /Districts Pharmacists, Lab technician etc.


To support states for undertaking Active Case Finding for diagnosis of TB Patients and to fulfill the gaps in diagnostics related to access under the diagnostics policy of NTEP, Programme has procured 45 Medical Mobile Vans. The Mobile Vans have CBNAAT Machine installed on the van itself to facilitate early diagnosis of MDR-TB and TB in high risk population through Active Case Finding. Apart from CB-NAAT machine, vans are fitted with Gen-set, Refrigerator, UPS, Printer, Air Conditioner etc to meet the requirement of CB-NAAT machines.


The programme has now implemented a logistics and supply chain management solution called the Nikshay Aushadhi to enable real time visibility into stock status at all levels and enable forecasting, quantification & further distribution of TB drugs and diagnostics. A synopsis of all related activities pertaining to drug management is now available to all the stakeholders in just a click.


The expansion of diagnosis and treatment services with newer tools and strategies to private sector will be the key to achieve our success of reaching everyone. Let us all pledge and join hands to end TB in India by 2025.


OUR SERVICES

Procurement and Supply Chain Management

It is a Centralised Activity being undertaken by PSM Unit through Procurement Agency selected by MoHFW at Central TB Division. Programme also undertakes direct Procurements particularly of Services and sometime of goods.










Sheffali Sharma

CTD Consultant


     

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Social support

 SOCIAL SUPPORT

The following schemes are applicable for various beneficiaries under National TB Elimination Programme and are provided as Direct Benefit Transfer (DBT) to the beneficiary:
Nikshay Poshan Yojana

Under this scheme, financial incentive of 500 INR/month for nutritional support is being provided to all TB patients notified under the programme in public and private sector, for the entire duration of treatment.

Transportation support for Patients in Tribal/hilly/difficult areas

TB patient in a notified Tribal/hilly/difficult area is eligible for 750 INR to cover travel costs of patient and attendant at the time of notification.

Honorarium to Treatment Supporter

To be disbursed upon completion or cure of TB patients. For Drug Sensitive TB patients, INR 1000 per TB patient is being provided. Similarly, for Drug Resistant TB patients, INR 5000 per TB patient, wherein 2000 INR for Intensive Phase and 3000 INR for Continuation phase is provided.

Informant Incentive for notification

An incentive of Rs 500 will be provided to any informant who refers presumptive TB cases to the public sector health facility and gets diagnosed as TB

Private provider incentive

Incentive of 1000 INR provided to Private providers for notification and reporting of treatment outcome. It is paid in 2 installments - 500 INR at notification and 500 INR on reporting treatment outcome.


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Information on tuberculosis

 INFORMATION ON TB

TB is of two types- Pulmonary and Extra pulmonary.

  • TB of the lungs is called Pulmonary TB and accounts for 80% of all TB cases.
  • TB affecting any other part/organ of the body like brain, lymph nodes, bones, joints, kidneys, larynx, intestines, eyes etc. is called Extra-pulmonary TB.

  • Only microbiologically confirmed pulmonary TB patients are infectious.
    Patients can suffer from both pulmonary and extra-pulmonary TB simultaneously.

  • Although TB is an infectious disease, all forms of TB are not infectious.
  • When a pulmonary microbiologically confirmed TB patient coughs or sneezes, TB bacteria spread into the air as droplets. People nearby may breathe in these bacteria and become infected.
  • An infectious case of TB, if untreated, can infect 10-15 people in one year.
  • Extra-pulmonary TB is not infectious.
  • TB does not spread through handshakes, using public toilets, sharing food and utensils, blood transfusion and casual contact.
  • TB is not a hereditary disease

  • In most people who breathe in TB bacteria the body's immune system is able to fight the TB bacteria and stop them from multiplying. This is called TB infection. People who are infected with TB do not feel sick, do not have any symptoms and cannot spread TB.
  • If an infected person's immune system cannot stop the bacteria from multiplying, the bacteria eventually cause symptoms of active TB which is called TB disease. Only 10% of all people with TB infection may suffer from the TB disease.
  • People with conditions like HIV, Diabetes Mellitus, Malnutrition and those on treatment with immunosuppressant drugs (anti-cancer, corticosteroids etc) are at a greater risk of developing TB disease once infected.
  • Close prolonged contact with a sputum positive pulmonary TB patient.
  • Overcrowding
  • Smoking
  • HIV infection
  • Malnutrition
  • Diabetes Mellitus
  • Patients on immunosuppressive drugs (anti- cancer, Corticosteroids etc.)
  • Certain lung diseases like Silicosis
  • TB can occur at any age but is commonly seen in persons between 15-45 years of age which is the economically productive age group.
  • Disease occurs in both the genders. However, males are affected more as compared to females.
  • Symptoms of TB are specific to the site affected although there are some symptoms common to all types of TB

    Symptoms of Pulmonary TB are:

  • Persistent cough for 2 weeks or more
  • Chest pain
  • Shortness of breath
  • Blood in sputum

  • Symptoms of Extra Pulmonary TB depend on the site/organ involved.
  • Brain TB- Meningitis
  • Lymphnode TB-Enlarged Lymphnodes
  • Bone TB- Destruction of bones and Joints
  • Abdominal TB –Intestinal Obstruction

  • Common symptoms:
  • Weight loss
  • Fatigue
  • Evening rise of temperature (Fever)
  • Night sweats
  • Tuberculosis is diagnosed by demonstrating TB bacteria in clinical specimen taken from the patient. While other investigations may strongly suggest tuberculosis as the diagnosis, they cannot confirm it.

  • Pulmonary TB is primarily diagnosed through Sputum smear microscopy. In this test patient’s sputum is examined under a microscope for the presence of TB bacteria.
  • In Extra pulmonary TB it is usually difficult to demonstrate TB bacteria, hence the diagnosis is made on the basis of clinical suspicion and special tests depending on the organ affected. e.g TB of the lymphnodes is diagnosed by a special test called FNAC (Fine Needle Aspiration Cytology)
  • In addition, CBNNAT machines are being used, which is a molecular test for diagnosing TB. In addition to the disease, it also mentions about the drug resistance to one of the potent anti TB drug Rifampicin.
  • Abnormalities on chest X ray may be suggestive but are never diagnostic of TB unlike smear examination in which TB bacteria are seen.
  • Several diseases can mimic TB on X ray such as Pneumonia, Silicosis, Bronchiectasis etc.
  • X rays do not help in differentiating between active and healed TB lesions. X rays therefore play only a supportive role in the diagnosis of pulmonary TB, mainly in cases where sputum smear result is negative
  • TB is completely curable if the prescribed drugs are taken regularly for the full duration.

    TB is treated through a combination of following drugs:

  • Isoniazid (INH)
  • Rifampicin
  • Pyrazinamide
  • Ethambutol
  • Streptomycin

  • Combination of drugs is administered to kill all the bacteria and prevent them from becoming resistant to one or more drugs.
    The treatment is given for 6-9 months.

    Very few people develop side-effects to anti TB drugs.

  • Most of these side-effects are minor and include vomiting, nausea, loss of appetite, joint pain, orange/red urine and skin rash. These can be easily managed with simple medicines and without stopping the anti TB drugs.
  • In some very rare cases serious side effects like deafness and jaundice may develop which may require temporary withdrawal of some of the anti TB drugs.
  • BCG (Bacille Calmette-Guerin) vaccine is currently the only vaccine available against TB.
  • Though BCG appears to reduce the risk of serious childhood forms of TB it is not effective in preventing TB in adults and children.
  • In the absence of an effective vaccine the only way to prevent TB is by early detection and treatment of infectious TB patients.
  • Patients with sputum positive pulmonary disease should cover their mouth while coughing, sneezing and talking to reduce the transmission of TB bacteria.
  • HIV is the strongest risk factor for tuberculosis among adults as it debilitates the immune system.
  • An HIV positive person is 20-40 times more likely to develop TB disease once infected with TB bacilli as compared to an HIV negative person.
  • TB is curable in HIV co-infected patients with the same medicines which are used to treat HIV negative TB patients.
  • However, HIV/TB co-infected patients require other medications like Antiretroviral therapy (ART) and Co-trimoxazole preventive therapy (CPT) to prevent other opportunistic infections.
  • Multidrug-resistant TB (MDR-TB) is defined as the disease caused by TB bacilli resistant to at least isoniazid and rifampicin, the two most powerful anti-TB drugs.
  • MDR TB, like all drug resistance TB, is a man made phenomenon caused by irregular or inadequate treatment when Patients do not take all their medicines regularly for the required period.
  • Health care providers prescribe inappropriate treatment regimens
  • The quality and supply of drugs is unreliable.
  • MDR TB is diagnosed through a special test called culture and drug susceptibility testing (C & DST) which can be performed by some specialized laboratories.

  • Conventional C & DST (also called solid C & DST) takes 3-4 months to diagnose MDR TB.
  • Newer rapid diagnostics for MDR TB are now available, like liquid C & DST, and molecular tests (CBNAAT & Line probe assay) which give results much earlier.
  • RNTCP or the Revised National Tuberculosis Control Program is the Tuberculosis Control Initiative of the Government of India.

  • It is based on DOTS- the global TB control strategy recommended by WHO.
  • The program was launched in 1997 and expanded to the entire country in 2006.
  • Programme has now been renamed as National TB Elimination Programme (NTEP)
  • Under NTEP the treatment is available free of cost at all government and identified private and NGO health facilities called as treatment centres. There are about 4 lakh such centres in the country.

  • Once the diagnosis of TB is confirmed the patient is treated with a standardized regimen which is based on past history of treatment for TB.
  • The regimen is given in 2 phases – Intensive phase (IP) and Continuation phase (CP)
  • ‘New TB patients’ i.e. patients who have never been treated for TB in the past (both pulmonary and extra-pulmonary) are treated for 6 months with the following regimen:
  • Cap Rifampicin, Tab Isoniazid, Tab Pyrazinamide and Tab Ethambutol for 2 months i.e. IP followed by
  • Cap Rifampicin, Tab Isoniazid and Tab. Ethambutol for 4 months i.e. CP.
  • All drugs are given on daily basis in FDC’s (Fixed Drug Combination). Total pill burden is reduced to make it more convenient for the patients.
  • The only criteria for becoming a treatment provider is that he/she should be acceptable to the patient and accountable to the health system.
    The identified treatment providers are given adequate training on administration of drugs, identification of adverse reactions, follow up and retrieval of the patient in case of treatment interruption.

    Treatment providers include

  • Staff of the health system (Doctors, Nurses, MPW, ANM, pharmacists etc)
  • NGOs
  • Private practitioners
  • Community volunteers – family member, Teachers, religious leaders, anganwadi workers, dais, ASHAs, Shop owners, cured TB patients etc.
  • Once a patient has been diagnosed to be suffering from TB a home visit is undertaken by the health worker for address verification and for counseling and educating the patient and family members on the disease and importance of regular treatment.
  • Contact details of the patient and a responsible family member/neighbor/friend/relative are recorded on the patient’s treatment card in case the patient interrupts treatment.
  • If a patient misses a dose the DOT provider contacts the patient by a house visit and encourages him to return for treatment. In case the DOT provider fails to retrieve the patient the supervisory staff (i.e. the Senior TB supervisor, Medical Officer etc.) are informed for taking necessary action.
  • In addition, ICT interventions like 99 DOTS are being used by the programme for adherence monitoring.
  • Under NTEP there is a provision of ‘Transferring Out’ to ensure continuity of treatment if a patient has to shift his residence to an area which is outside the TB unit in which he/she has been registered. This could be another district or even another State anywhere in the country.
  • The treatment is continued at the treatment centre nearest to the new residence of the patient.
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    Symptoms of Tuberculosis

     SYMPTOMS OF TB


    Are you experiencing any of the following symptoms?
    avatarFever for more than 2 weeks
    avatarCoughing for more than 2 weeks
    avatarCoughing up blood
    avatarNight Sweats
    avatarUnexplained Weight Loss



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    Side effects

     SIDE EFFECTS

    Important Information :
    • Not Everyone suffers from Unpleasant Side Effects.
    • If you get side effects, mild ones will disappear with time. If you continue to experience unpleasant feelings or side effects, please inform your Treatment supporter, ASHA, ANM or doctor.
    • Early action prevents side effects.
    • Irregular and inappropriate TB treatment makes you prone to develop Drug Resistant TB
    • Don't Share your Drugs or advice treatment to others.
    • Don't Smoke or Drink alcohol as it can worsen the side effects.
    • Always carry your TB Patient-ID card with you.

    List Of Side Effects

    • Take medicines embedded in banana
    • Do not take all the medicines together
    • Take medicines with little water or milk at bed time
    • Avoid smoking and drinking alcohol
    • Stay hydrated (drink enough water)
    • Eat nutritious food
    • Eat nutritious food
    • Do not stop or reduce the dose of anti-TB medicines on your own
    • Inform your Treatment Supporter, healthcare worker or doctor without any delay
    • May indicate harm to liver
    • Inform and consult your Treatment Supporter, healthcare worker or doctor
    • Can be prevented by taking vitamin B6 on doctor's advice
    • Usually mild and subsides on its own
    • May be due to flu infection.Inform and consult your Treatment Supporter, healthcare worker or doctor
    • Apply moisturizing cream
    • Do not expose rashes to sunlight
    • Rashes usually subside with time
    • If rash develops in the mouth or nose or involves very large body area or is associated with fever;inform and consult your Treatment Supporter, healthcare worker or doctor immediately
    • Inform and consult your Treatment Supporter, healthcare worker or doctor immediately
    • Usually resolves on stopping Ethambutol
    • If Ethambutol is stopped, it needs to be replaced by another drug to fully treat TB
    • Usually harmless', 'Can be treated with pain killers
    • Inform and consult your Treatment Supporter, healthcare worker or doctor immediately'
    • Inform and consult your Treatment Supporter, healthcare worker or doctor
    • Inform and consult your Treatment Supporter, healthcare worker or doctor
    • Needs to be evaluated and can be treated with nutritious food and appropriate drugs
    • Inform and consult your Treatment Supporter, healthcare worker or doctor immediately
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    Nutrition Advice

     Nutritional assessment, counseling and support are integral parts of TB care. Undernutrition is an established risk factor for progression of latent TB infection to active TB, increases the risk of severe disease, death, drug toxicity, drug malabsorption & relapse after cure. Moreover, TB leads to weight loss, wasting and worsening of nutritional status. Therefore, Undernutrition and tuberculosis (TB) have a bidirectional relationship.


    No single food group contains all nutrients. Not all foods in the same group have the same nutritive value. a balanced diet therefore combines different food groups and different types of foods. Encourage intake of locally available cereals, millets, pulses, nuts, fruits and green leafy vegetables, dairy products, fish and flesh foods (if culturally acceptable).

    Nutritional Value Of Common Foods

    Cereals and millets

    Cereals include rice, wheat and maize and millets include sorghum (jowar), pearl millet (bajra), finger millet (ragi), etc. Use foods containing whole grains as much as possible.

    • Nutritive value : Main source of energy: about 350 kcal per 100 gm on an average. They also provide proteins, ranging from 7 gm to 12 gm %, B vitamins, fiber and potassium. Cereal proteins are deficient in some amino acids and combining them with pulses can help provide a good quality protein for vegetarians.
    • Special mention : Pearl millet (Bajra) has higher fat content. Finger millet (Ragi) is rich in calcium and a good source of iron.
    Pulses

    The common pulses are Bengal gram (chana), red gram (tuvar/arhar), green gram (mung), black gram (urad), lentils (masur) and soya bean.

    • Nutritive value : They are high in protein (20 to 25 gm %.) and of special value to vegetarians.
    • Special mention : Germination of pulses(sprouting) improves nutritive value and can decrease cooking time. Soya bean has 20% fat and up to 37% protein making it a high calorie and high protein food.
    Nuts and oil seeds

    These include groundnuts, coconut, mustard seeds, sesame seeds, cashew nut, almonds, sunflower seeds and many others from which cooking oil is extracted.

    • Nutritive value : Contain high amount of fats(40-60%) and proteins (absent when oil is extracted). Excellent as an energy and protein rich snack for patients with undernutrition. Of special value to vegetarians as a source of protein.
    • Special mention : Groundnuts are as good as costlier forms of nuts, but should preferably be taken in a roasted and a deskinned form to reduce the risks due to contamination. Some persons may be allergic to nuts and these should be then avoided.
    Vegetables

    Vegetables include leafy vegetables, roots and tubers (e.g. potatoes), other vegetables such as gourds, brinjal, tomatoes,beans, peas, cauliflowers, onions, etc. They can be taken generously in diet and seasonal vegetables should be eaten as much as possible.

    • Nutritive value : They contain carbohydrates (content varies from 4-25%), and are protective foods and good sources of vitamins A and C, folate, iron and magnesium, fibre.
    • Special mention : Green leafy vegetables like spinach, amaranth, fenugreek are high in fibre Vitamin A and C, calcium and iron. Potatoes are energy rich & a good source of vitamin C.
    Fruits

    Fruits include Bananas, mango, papaya, guava, citrus fruits (including lemon, oranges), melons, apples and pears, berries.

    • Nutritive value : Fruits are good source of vitamins A and C and potassium.
    • Special mention : Bananas are a good source of energy (about 100 kcal per banana), magnesium and potassium (deficient in patients with severe undernutrition). Gooseberry and guavas have high vitamin C content, while all yellow fruits are good sources of vitamin A (low levels are seen in TB patients, while low levels in household contacts might increase TB risk).
    Milk and dairy products

    These include milk, curds, cottage cheese (paneer), processed cheese.

    • Nutritive value : They are a source of protein, fat, calcium, vitamins A and D, B vitamins (including B12). Depending on the source (human, buffalo, goat), the protein content ranges from 3-4 gm per 100 gm, fat content is 4 – 8%. Protein, fat content of cheese is higher. 100 ml of milk provides 70 to 110 kcal.
    • Special mention : Some persons have lactose intolerance and may have flatulence and diarrhoea after consumption of milk and dairy products.
    Eggs, Fish, Poultry and Meat

    These include milk, curds, cottage cheese (paneer), processed cheese.

    • Nutritive value : One egg weighing about 60 gm provides 6 gm of proteins, 6 gm of fat and supplies about 90 kcal. Meat and fish have 15 – 25% protein of good quality, iron and zinc. Fish fat is rich in unsaturated fatty acids and Vitamin A and D.
    • Special mention : Egg protein is of high biological value and is the reference protein to which proteins (plant, meat, fish) are compared. One egg can substitute for 50% of pulse consumption in terms of protein intake.
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